DSIP 5 mg lyophilised peptide vial with teal flip-off cap and white label

NovaPep

Buy DSIP Peptide Australia: DSIP 5mg and 10mg Research Vials and Nasal Spray (Delta Sleep-Inducing Peptide)

$39AUD, GST included

In stock in Australia, batch certificate ready

Certificate of analysis published for every batch
Third-party HPLC purity and MS identity testing
Dispatched same day before 3pm cut-off, tracked Australia-wide
Research use only, sold to adults aged 18 and over

Buy DSIP peptide online in Australia as a 5 mg or 10 mg research vial or a ready-made 10 mL nasal spray, tested on every lot. DSIP peptide, or delta sleep-inducing peptide, is the nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, which Schoenenberger and Monnier isolated in Basel in 1977. Its receptor has never been identified, and that open question keeps it in active use for sleep and stress-axis research. It is available online in Australia in three formats, a 5 mg vial, a 10 mg vial or a ready-to-use 10 mL nasal spray, each kept in local stock. The identity figures to verify are C35H48N10O15, 848.8 g/mol and CAS 62568-57-4. Mass spectrometry confirms every powder and spray lot and HPLC measures its purity, and you can view the certificate before checkout. Plan your diluent volume with the peptide calculator, and consider adding Selank to the same parcel as a second neuropeptide. Vials arrive as dry powder, so order bacteriostatic water too, whereas the spray already contains 10 mg dissolved at 1 mg/mL. Keep sealed vials at -20 °C. Sold as a research reagent to adults aged 18 or over.

For laboratory research use only. Not for human or veterinary use. Not TGA approved. See the NovaPep research use policy.

What Is DSIP Peptide?

DSIP is short for delta sleep-inducing peptide, a brain peptide of nine amino acids that was originally associated with deep, slow-wave sleep and today is studied chiefly as an open puzzle in neuroendocrinology. It is compact, water soluble and simple to synthesise. Yet nearly five decades after it was named, researchers still disagree about what it does and which target it acts on. DSIP is for sale in Australia as a 5 mg or 10 mg research vial or a 10 mL nasal spray, ready to order online from local stock.

The DSIP supplied here is a synthetic copy of a factor that Guido Schoenenberger and Marcel Monnier extracted in 1977 from the cerebral venous blood of rabbits held in electrically induced sleep. The name reflects the slow delta waves recorded in those animals. Sequencing followed, and immunoreactive forms were later reported in the plasma, pituitary and hypothalamus of several species.

Where the word delta comes from

Non-REM sleep is divided into stages, and the deepest is dominated by delta waves, which are big, slow electrical rhythms of around 0.5 to 4 cycles per second that an EEG detects over the cortex. In the first rabbit experiments the peptide seemed to boost exactly this activity, which is how it got its name. Later attempts to replicate that effect were patchy, and the name has lasted longer than the evidence behind it.

Inside the DSIP molecule

With tryptophan at position 1, two acidic residues and a glutamate at the C-terminus, DSIP carries a negative charge at neutral pH and dissolves easily. Tryptophan absorbs strongly in the ultraviolet, producing a clear HPLC signal. The glycine-rich centre of the chain is flexible, and the unprotected N-terminus is open to aminopeptidases, which explains why the peptide degrades quickly in biological media.

How DSIP Works, and Why Nobody Is Sure

Most neuropeptides follow a familiar route. A gene codes for a larger precursor, enzymes cut the active peptide from it, and the peptide works through a receptor that can be cloned and examined. DSIP fails on every count. No gene has been found, no precursor has been confirmed and no receptor has been isolated. Vladimir Kovalzon and Tatyana Strekalova captured this in the title of their 2006 review in the Journal of Neurochemistry, which described DSIP as a still unresolved riddle.

Even so, antibodies raised against DSIP detect reactive material in blood and brain tissue. The problem is that an antibody signal does not prove the exact nine-residue chain is there. The protein GILZ (gene TSC22D3) is a familiar case, as it carries the alias DSIPI (DSIP immunoreactor) only because an anti-DSIP antibody happened to bind it. GILZ is a glucocorticoid-induced leucine zipper protein, completely different in structure and role, and that old alias still muddles database results.

Because no receptor has been cloned, mechanism work on DSIP is built from indirect readouts. Studies track EEG patterns, stress hormones and pituitary release rather than binding to a known target. That makes well characterised material and solid controls more important than usual.

DSIP Research: What Studies Have Looked At

The sequence traces to a PNAS paper published in March 1977, where Schoenenberger and Monnier described the nonapeptide and made it synthetically together with fragments and analogues. They found that only the synthetic native chain increased delta and spindle EEG activity in rabbits. Those results built on sleep-factor experiments Monnier had published during the 1960s. Shop DSIP online in Australia for this research, knowing each lot has been checked for identity and purity.

That unresolved mechanism is exactly why DSIP is still studied. Early EEG studies in rats and rabbits produced inconsistent findings, and subsequent rodent work turned to stress responses, somatostatin, and pituitary release of corticotropin and luteinising hormone. With no dedicated receptor ever cloned, each carefully designed experiment contributes new data, and solid controls with well-characterised material count for more than usual. You will find it in our nootropic peptides and longevity peptides collections, listed as a research reagent and not as a medicine.

Measuring DSIP in the lab

For a lab, this is the most valuable lesson in the literature. If you are measuring endogenous DSIP or following the synthetic peptide in tissue or medium, an immunoassay by itself is not enough. Confirm by LC-MS against a standard of known identity, ideally taken from the same lot used to treat the cultures, so the WAGGDASGE mass and retention time can be matched directly. Skip that step and a positive ELISA could be picking up a cross-reacting protein instead of the peptide you meant to measure.

DSIP Specifications

Product name	DSIP (delta sleep-inducing peptide)
Formats	5 mg vial, 10 mg vial, 10 mL nasal spray (10 mg)
Sequence	Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, a linear nonapeptide with free termini
Residue count	9 amino acids
Formula	C35H48N10O15
Molar mass	848.8 g/mol
CAS	62568-57-4
Physical form	Lyophilised powder under a flip-off cap in the vials, and a 1 mg/mL solution in a 10 mL pump bottle for the spray
Quality testing	Mass spectrometry for identity and HPLC for purity on both vial and spray lots, one certificate per lot
In the box	A single vial (5 mg or 10 mg) without diluent, or a single spray bottle containing 10 mg in 10 mL, with bacteriostatic water for the vials sold separately
Storage conditions	Closed vials at -20 °C, dry and dark. The spray and reconstituted vials at 2 to 8 °C
Stock status	In stock
Intended use	In vitro laboratory research only

Pick the DSIP format that matches your protocol, powder when you want to set the concentration yourself or the spray when the design follows the intranasal literature. Every format is held in Australia and arrives with its lot certificate.

Know what to look for on the certificate, namely a measured mass consistent with 848.8 g/mol and one main HPLC peak, with purity stated for that particular lot. Vial lots and spray lots each have a separate document in the COA library, and the spray certificate covers the same identity and purity tests performed on the solution lot itself.

Handling and Storage of DSIP

To prepare a vial, allow it to reach room temperature, let the diluent run softly down the glass and swirl, and the charged residues will help it dissolve quickly. Adding 2.5 mL of bacteriostatic water to the 5 mg vial produces 2 mg/mL, and other volumes can be worked out with the peptide calculator. The spray needs no preparation. DSIP for sale in Australia leaves our shelves by tracked post, so it reaches your bench in good condition.

Store sealed vials at -20 °C, shielded from light. DSIP breaks down relatively fast once dissolved, so keep reconstituted vials at 2 to 8 °C, split them into aliquots and use them without delay, and place the spray bottle in the fridge as soon as it arrives. Thaw only the aliquot you need for that day, because repeated warming and cooling hastens the loss of intact peptide.

DSIP Compared With Selank

DSIP is a nine-residue chain of uncertain origin, used in sleep architecture and neuroendocrine models. Selank, by contrast, is a seven-residue tuftsin analogue examined in rodent models of anxiety-like behaviour and GABA-related gene expression. Go with DSIP for questions about sleep and the stress axis, and Selank for cytokine and GABA readouts.

Both come as a vial or a 10 mL spray, and the Spray Research Kit groups the DSIP, Selank and Semax sprays together for intranasal studies. Labs working on pineal rhythm designs frequently add Epitalon too, as its melatonin research overlaps with sleep models.

Other Names for DSIP

DSIP means delta sleep-inducing peptide, which is sometimes printed without the hyphen as delta sleep inducing peptide. In sequence databases it appears as WAGGDASGE, and its full chemical name opens with L-tryptophyl-L-alanyl-glycyl-glycyl. Older papers also mention a phosphorylated variant carrying a phosphate on the serine at position 7. Whichever of these names you use, the molecule supplied is the 848.8 g/mol chain registered under CAS 62568-57-4.

Buy DSIP Peptide Online in Australia, Vials, Spray and Legal Status

Few compounds in our range come in three physical forms, and DSIP is one of them. The 5 mg and 10 mg vials contain a dry white cake beneath a teal flip-off cap, and the 10 mL bottle, fitted with a white pump actuator and silver collar, holds the same 10 mg already dissolved. That spray is also one of three bottles packed in our Selank, Semax and DSIP spray kit.

The 5 mg vial suits pilot runs or method development because it is the simplest fill to finish once reconstituted. For established protocols, the 10 mg vial lowers the cost per milligram. Both arrive lyophilised and require a diluent.

The 10 mL nasal spray contains the same 10 mg pre-dissolved at a fixed 1 mg/mL beneath a pump actuator. The small premium over the 10 mg vial covers the ready solution and bottle, not additional peptide. It fits intranasal-route designs, although its strength cannot be changed. Ordering several units together keeps a study on a single lot and certificate wherever stock allows. Sales of DSIP are limited to adults aged 18 or above.

Almost fifty years on, DSIP in Australia has no clinical standing. As of October 2026 it does not appear in the Poisons Standard, and searching the October 2026 instrument for both DSIP and delta sleep-inducing peptide gave no results, so no schedule applies. Not being scheduled does not make a peptide an approved therapeutic good, and the TGA requires listing on the Australian Register of Therapeutic Goods before a peptide can be supplied for any therapeutic purpose. In reality, DSIP peptide Australia demand is served by research suppliers, not pharmacies.

NovaPep stocks DSIP Australia supply in the format your protocol requires, vials or the DSIP nasal spray, all kept locally as research reagents for laboratory work. Only adults aged 18 or over may order, and no format is intended for human or veterinary use. Before opening a spray bottle, it is worth reading our storage guide for peptides in solution.

Ordering DSIP Near Me and Delivery Across Australia

No shop stocks DSIP over the counter. NovaPep operates online only and sends tracked parcels from Australian stock to every state, dispatching the same day for orders paid before 3pm on business days. Regional timing is listed on our delivery page.

DSIP at a Glance

A nine-residue peptide from 1977

DSIP is a nonapeptide first extracted in Basel from rabbit blood. It is named after the delta brain waves recorded in those studies, and its receptor remains unidentified.

Buy a vial or a spray online

Pick a 5 mg vial, a 10 mg vial or a 10 mL spray. The vials need bacteriostatic water, while the spray is ready as delivered.

Sleep and hormone research

Used in EEG, pituitary hormone and stress-response studies in tissues and animals, and supplied for laboratory research only.

Not the same as Selank

Selank is a tuftsin analogue researched for cytokine and GABA readouts, whereas DSIP is an unrelated neuropeptide linked to sleep studies.

Work quickly once dissolved

Freeze sealed vials at -20 °C. DSIP degrades fairly quickly in solution, so keep it refrigerated and work from small aliquots.

Checked before it ships

Each vial and spray lot is tested by mass spectrometry and HPLC, and its certificate is published under the lot number.

DSIP FAQ

What is DSIP peptide?

DSIP, or delta sleep-inducing peptide, is a nine amino acid chain, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, first isolated from rabbit blood in 1977. It was named after the delta waves of deep sleep. No gene, precursor or receptor has been confirmed, so it remains an open research question in neuroendocrinology.

How does DSIP work?

Nobody knows for certain. No receptor has been isolated, so studies rely on indirect readouts such as EEG activity, stress hormones and pituitary release of corticotropin and luteinising hormone in rodent models. Early EEG findings in rats and rabbits were inconsistent, which is why it is still investigated.

What is the process to order DSIP online in Australia?

Choose the 5 mg vial, the 10 mg vial or the 10 mL nasal spray on this page, add your pick to the cart and check out. All formats leave from Australian stock, and orders paid before 3pm on a business day are dispatched that day. The vials require a diluent such as bacteriostatic water, but the spray does not.

Is a certificate of analysis supplied with DSIP?

Yes, for all three formats. Vial lots and spray lots are tested separately, with mass spectrometry for identity and HPLC for purity, and each certificate is posted in the COA library. Check the lot number on your vial or bottle against the document before you start your first experiment.

Which should I buy, DSIP or Selank?

DSIP suits sleep architecture, pituitary hormone and stress-axis models, while Selank suits GABA-related gene expression and cytokine studies. Their sequences are unrelated. If both will be used by the intranasal route, the Spray Research Kit packs the DSIP, Selank and Semax sprays into one order.

Does the DSIP nasal spray contain the same peptide as the vials?

It does. The spray holds the identical DSIP sequence found in the vials, 10 mg dissolved in 10 mL at 1 mg/mL. Only the format differs, since powder lets you pick the concentration whereas the spray is fixed but needs no mixing. Both are research reagents meant for laboratory use only.